Utilization of cassava residue by-product as a C/N source for effective production of prodigiosin via microbial fermentation

Main Article Content

Utilization of cassava residue by-product as a C/N source for effective production of prodigiosin via microbial fermentation

Tác giả

Nguyễn Văn Bốn
Nguyễn Thị Huyền
Trần Thị Hà Trang
Đỗ Văn Chung
Phạm Thị Huyền Thoa
Nguyễn Anh Dũng

Tóm tắt


Recently, prodigiosin (PG), a red pigment compound produced mainly by Serratia marcescens, has been applied in various fields. Thus, this microbial pigment has been extensively studied for biosynthesis and potential biofunctions. This study aimed to utilize cassava residue by-product (CRBP) as a C/N source for the eco-friendly production of PG via fermentation. PG was produced at the highest yield when Serratia marcescens TNU1 was grown in the medium containing 1.5% CRBP, 0.2% casein, 0.05% MgSO4, and 0.1% K2HPO4, with an initial pH of 7.0, and fermentation was performed at 27.5°C for two days. Additionally, PG scale-up bioproduction was investigated in a 14 L bioreactor system, and PG was produced at a high yield (6450 mg/L) in a short fermentation time (12h). This study suggests CRBP is a novel and potential C/N source for the cost-effective bioproduction of PG.


Article Details

Chuyên mục
Khoa học Tự nhiên & Công nghệ
Tiểu sử của Tác giả

Nguyễn Văn Bốn

Viện Công nghệ Sinh học và Môi trường, Trường Đại học Tây Nguyên;
Tác giả liên hệ: Nguyễn Văn Bốn; ĐT: 0842458283, Email: nvbon@ttn.edu.vn.

Nguyễn Thị Huyền

Viện Công nghệ Sinh học và Môi trường, Trường Đại học Tây Nguyên

Trần Thị Hà Trang

Viện Công nghệ Sinh học và Môi trường, Trường Đại học Tây Nguyên

Đỗ Văn Chung

Viện Khoa học Kỹ thuật Nông Lâm nghiệp Tây Nguyên

Phạm Thị Huyền Thoa

Khoa Khoa học Tự nhiên và Công nghệ, Trường Đại học Tây Nguyên

Nguyễn Anh Dũng

Viện Công nghệ Sinh học và Môi trường, Trường Đại học Tây Nguyên

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